No matter how good you think the guacamole is, you shouldn’t give it to your dog. Avocados contain a substance called persin. It’s harmless for humans who aren’t allergic, but large amounts might be toxic to dogs. If you happen to be growing Avocados at home, keep your dog away from the plants. Persin is in the leaves, seed, and bark, as well as in the fruit. Home Sweet Home Pet Sitters wants you to keep your pet safe!